Quantitative Methods for Assessing Drug Synergism
نویسندگان
چکیده
منابع مشابه
Revisiting the isobole and related quantitative methods for assessing drug synergism.
The isobole is well established and commonly used in the quantitative study of agonist drug combinations. This article reviews the isobole, its derivation from the concept of dose equivalence, and its usefulness in providing the predicted effect of an agonist drug combination, a topic not discussed in pharmacology textbooks. This review addresses that topic and also shows that an alternate meth...
متن کاملPerspectives in Pharmacology Revisiting the Isobole and Related Quantitative Methods for Assessing Drug Synergism
The isobole is well established and commonly used in the quantitative study of agonist drug combinations. This article reviews the isobole, its derivation from the concept of dose equivalence, and its usefulness in providing the predicted effect of an agonist drug combination, a topic not discussed in pharmacology textbooks. This review addresses that topic and also shows that an alternate meth...
متن کاملAn R Package for Assessing Drug Synergism/Antagonism
This introduction to the R package mixlow is a (slightly) modified version of Boik and Narasimhan (2010), published in the Journal of Statistical Software. Synergistic and antagonistic drug interactions are important to consider when developing mixtures of anticancer or other types of drugs. Boik, Newman, and Boik (2008) proposed the MixLow method as an alternative to the Median-Effect method o...
متن کاملislanding detection methods for microgrids
امروزه استفاده از منابع انرژی پراکنده کاربرد وسیعی یافته است . اگر چه این منابع بسیاری از مشکلات شبکه را حل می کنند اما زیاد شدن آنها مسائل فراوانی برای سیستم قدرت به همراه دارد . استفاده از میکروشبکه راه حلی است که علاوه بر استفاده از مزایای منابع انرژی پراکنده برخی از مشکلات ایجاد شده توسط آنها را نیز منتفی می کند . همچنین میکروشبکه ها کیفیت برق و قابلیت اطمینان تامین انرژی مشترکان را افزایش ...
15 صفحه اولQuantitative Methods for Assessing NIS Populations for Invasiveness
Plant species, as a taxonomic group can not be judged to be invasive. However, there are some plant species that have traits that allow a subset of their populations to be invasive. That is, there will always be variation in invasiveness of a plant species across the environments where it has become established regardless of its notoriety as an invasive species. In fact, there may be many envir...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Genes & Cancer
سال: 2011
ISSN: 1947-6019,1947-6027
DOI: 10.1177/1947601912440575